An analysis of CT parameters in patients with advanced Kashin-Beck disease knee arthritis

Abstract:

Objective To analyze the characteristics of computed tomography（CT） parameters in patients with advanced Kashin-Beck disease（KBD） knee arthritis and to provide a reference for the diagnosis of this disease and the preoperative planning of knee arthroplasty.Methods Patients diagnosed with KBD knee arthritis in our hospital from January 2018 to December 2022 were retrospectively analyzed，and the patients with advanced knee osteoarthritis in the same period were selected as controls. The CT parameters of patients’ knee joint were analyzed by Mimics software for measurement of knee-joint osteophyte volume，the number of loose bodies within the articular cavity，femoral mediolateral（FML） diameter，femoral medial anteroposterior（FMAP） diameter，femoral lateral anteroposterior（FLAP） diameter，tibial mediolateral（TML） diameter，tibial anteroposterior（TAP） diameter，tibial medial anteroposterior（TMAP） diameter，and tibial lateral anteroposterior（TLAP） diameter，and the FML/FMAP，FML/FLAP，TML/TAP，and TMAP/TLAP ratios were calculated.Results A total of 70 patients were included，with 32 patients in the KBD group and 38 patients in the osteoarthritis group. There were no significant differences in sex distribution，average age，and body mass index between the two groups （P>0.05）. In the KBD group，patients often developed multi-compartment arthritis in the knee joint with a large number of osteophytes around the joint，and significant subchondral osteosclerosis. The KBD group had significantly higher volume of osteophyte，number of loose bodies within the articular cavity，and FML/FLAP and TMAP/TLAP ratios than the control group（P<0.05）.Conclusion Patients with advanced KBD knee arthritis have more significant degenerative signs and smaller FLAP and TLAP diameters. These imaging characteristics can be useful for the preoperative planning of knee arthroplasty in patients with advanced KBD knee arthritis.