Research progress of plasma inflammatory cytokine adsorption in the treatment of sepsis

Abstract:

Sepsis and septic shock are common in intensive care units，with more than 18 million cases of severe sepsis worldwide each year. According to the epidemiological survey abroad，the case fatality rate of sepsis has exceeded that of myocardial infarction， so sepsis has become the main cause of death of non-cardiac patients in intensive care units. Medical advances have led to more and more innovative treatments for sepsis. Continuous blood purification is gradually emerging as a crucial early treatment modality for septic patients，while extracorporeal blood adsorption is also gaining attention for its therapeutic value in septic patients. This article aims to summarize the research progress of plasma inflammatory cytokine adsorption in the treatment of sepsis in recent years， as well as the common extracorporeal blood adsorption techniques that have been reported in existing research or applied clinically along with their research advances，thus providing a reference for better understanding its application value in clinical treatment and improving the prognosis，and offering help for the treatment of patients with sepsis and septic shock.