Comparative study of ureteral occlusion device combined with ureteroscopic holium laser lithotripsy in the treatment of ureteral calculi

Abstract:

Objective：To evaluate the clinical efficacy and safety of INNOVEX TMIVX-SC10 ureteral occlusion device in the uretero－scopic holmium laser lithotripsy. Methods：Totally 299 patients with unilateral ureteral calculi from January 2013 to August 2013 were enrolled in this study. They were randomly divided into 2 groups，group A（141 cases） applying ureteral occlusion device and group B（158 cases） not applying ureteral occlusion device during ureteroscopic holmium laser lithotripsy. The success rate，calculus elimination rate，average operation time and complications were compared. Results：There was no statistically significant difference in overall calculi free rate between group A（90.1%） and group B（82.3%）（P=0.053）. There were statistically significant differences in calculi free rate for upper urethral calculi between group A（81.6%） and group B （62.0%）（P=0.046），but there was no difference for lower urethral calculi between two groups（P=1.000，0.590）. Average operation time of success cases were （36.2±13.4） min and （44.9±28.7） min with statically differences between two groups（P=0.002）. Average operation time of upper ureteral calculi stone were （39.2±12.0） min and （53.3±26.2） min with statically differences between two groups（P=0.010）. Average operation time of middle urethral calculi were （43.0±14.1） min and （45.3±20.0） min with statically differences between two groups（P=0.754）. Average operation time of lower ureteral calculi were （34.1±13.6） min and （41.1±28.5） min with statically differences between two groups（P=0.047）. Calculi free rates for upper urethral calculi in two groups were 96.8% and 80.6%，without statistically significant difference（P=0.104） and no statistically significant difference was found in calculi free rates for middle and lower ureteral calculi between two groups（P=1.000，0.479）. There was no difference in complication incidence between two groups. Conclusion：Ureteral occlusion device can significantly increase success rate and calculi free rate for upper ureteral calculi and can reduce operation time of ureteroscopy lithotripsy.